Fig. 6: Proteomics analysis verified that CEP70 participated in the regulation of acrosome and flagella formation.
From: Loss of CEP70 function affects acrosome biogenesis and flagella formation during spermiogenesis
A Flow diagram of testis TMT-label proteomics analysis of the WT and Cep70−/− mice (n = 3). B Volcano plot show the downregulated (FC < 1/1.3, blue) and upregulated proteins (FC > 1.3, red) in Cep70−/− mice testes compared with WT testes. C The heatmap of GO terms enriched in DEPs between the WT and Cep70−/− mice testes. D PPI network analysis revealed the biological processes of the DEPs between the WT and Cep70−/− mice testes. E Heatmap showing the discrepancy expression level of downregulated proteins between the WT and Cep70−/− mice testes.
