Fig. 3: YTHDF2 regulated the metastatic capacity of LUAD cells.

a, b Ectopic overexpression of YTHDF2 significantly promoted A549 and H1792 cell migration and invasive capabilities as examined by wound healing (a) and Transwell invasion (b) assays. Data are shown as means ± S.D.; *P < 0.05, **P < 0.01, and ***P < 0.001 compared with control cells. c, d Silencing of YTHDF2 by shRNA effectively inhibited A549 and H1792 cell migration and invasive capabilities. Data are shown as means ± S.D.; **P < 0.01 and ***P < 0.001 compared with control cells.