Fig. 7: YTHDF2 high expressed promoted progression and metastasis of lung cancer cells via AXIN1/Wnt/β-catenin signalling. | Cell Death & Disease

Fig. 7: YTHDF2 high expressed promoted progression and metastasis of lung cancer cells via AXIN1/Wnt/β-catenin signalling.

From: RNA m6A reader YTHDF2 facilitates lung adenocarcinoma cell proliferation and metastasis by targeting the AXIN1/Wnt/β-catenin signaling

Fig. 7

YTHDF2 facilitated the decay of AXIN1 m6A mRNA and results in the dereased AXIN1protein level.The decreased AXIN1 promote the activity of Wnt/β-catenin signalling and enhance the proliferation and migration of lung cancer.

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