Fig. 2: CircACSL1 is upregulated in myocarditis (MC). | Cell Death & Disease

Fig. 2: CircACSL1 is upregulated in myocarditis (MC).

From: Circular RNA circACSL1 aggravated myocardial inflammation and myocardial injury by sponging miR-8055 and regulating MAPK14 expression

Fig. 2

A The expression of circACSL1 was higher in MC patients (n = 22) compared with that in control volunteers (n = 20) as measured by qRT-PCR. B The expression of pre-mRNA ACSL1 showed no significant difference between MC (n = 22) and controls (n = 20). C The expression level of circACSL1 in the recovery phase decreased significantly compared with the acute phase in six MC patients (n = 6). D, E The dynamic changes of circACSL1 and Hs-TnT (pg/ml) levels were detected every day within the first week of onset in two MC patients (MC-01 and MC-02). F, G The dynamic changes of circACSL1 and NT-pro BNP (pg/ml) levels were detected every day within the first week of onset in two MC patients (MC-01 and MC-02). H The expression levels of circACSL1 in dilated cardiomyopathy (DCM) and MC. I circACSL1 was upregulated in the LPS-induced HCM inflammation model. Data were presented as mean ±SD. *p < 0.05; **p < 0.01; ***p < 0.001; ns (no significance) p > 0.05 (Student’s t test).

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