Fig. 1: Anemia phenotype in Gata2L359V/L359V embryos. | Cell Death & Disease

Fig. 1: Anemia phenotype in Gata2L359V/L359V embryos.

From: Gata2-L359V impairs primitive and definitive hematopoiesis and blocks cell differentiation in murine chronic myelogenous leukemia model

Fig. 1: Anemia phenotype in Gata2L359V/L359V embryos.

A Schematic of the Gata2-L359V knockin murine model. The L359V mutation was introduced into the ZF2, which is located in the exon 5 of the murine Gata2 gene. B Morphology of embryos and yolk sacs of different genotypes at E9.5 (left panel, scale bar 500 μm) and E10.5 (right panel, scale bar 500 μm). C O-dianisidine staining of hemoglobin in yolk sac erythrocytes (scale bar 500 μm).

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