Fig. 1: Xist expression in perinatal ovaries is essential for PF pool formation. | Cell Death & Disease

Fig. 1: Xist expression in perinatal ovaries is essential for PF pool formation.

From: Long non-coding RNA Xist regulates oocyte loss via suppressing miR-23b-3p/miR-29a-3p maturation and upregulating STX17 in perinatal mouse ovaries

Fig. 1: Xist expression in perinatal ovaries is essential for PF pool formation.

a qRT-PCR analysis of Xist expression at the indicated time points. Gapdh was used to normalize samples. b, c qRT-PCR analysis of Xist expression in newborn ovaries transfected with siXist (b), and Xist OE (c), relative to respective controls. d, e Representative images of DDX4 immunofluorescence staining (left) and quantification of follicles (right) in newborn ovaries transfected with siXist (d), and Xist OE (e). Scale bars: 50 μm. f, g qRT-PCR analysis of genes involved in PF survival and development in siXist (f), and Xist OE (g) transfected ovaries, relative to respective controls. Student’s t-test: *P < 0.05, **P < 0.01, ***P < 0.001.

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