Fig. 2: The coronary arteritis was mitigated after Il-37b injection in a KD mouse model. | Cell Death & Disease

Fig. 2: The coronary arteritis was mitigated after Il-37b injection in a KD mouse model.

From: IL-37b alleviates endothelial cell apoptosis and inflammation in Kawasaki disease through IL-1R8 pathway

Fig. 2

a Representative images from H&E staining at 28-day post-CAWS injection. Magnification: ×200. Scale bar = 100 μm. b–d The expression levels of vascular cell adhesion molecule 1 (VCAM-1), macrophage marker F4/80, and neutrophil marker were, respectively, determined using IHC staining in the endothelium of coronary arteries. Enlarged images of area of interesting (AOI) were indicated with a red arrow. Scale bar = 100 μm. e–g The expression levels of cytokines, adhesion molecules, and chemokines were detected in the mice heart section. Significance: *P < 0.05 vs. the PBS group, and #P < 0.05 vs. the CAWS group. N = 6 mice per group, and each experiment was conducted at least three times.

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