Fig. 6: LINC00473 promotes the growth of PA in vivo. | Cell Death & Disease

Fig. 6: LINC00473 promotes the growth of PA in vivo.

From: LncRNA LINC00473 is involved in the progression of invasive pituitary adenoma by upregulating KMT5A via ceRNA-mediated miR-502-3p evasion

Fig. 6: LINC00473 promotes the growth of PA in vivo.The alternative text for this image may have been generated using AI.

a Images of tumors formed in nude mice injected subcutaneously with PA cells (overexpression, control, or knockdown of LINC00473) were shown. b The volume of subcutaneous xenograft tumors. c Ki-67 and KMT5A immunohistochemical staining. d qRT-PCR was used to detect the expression of LINC00473, miR-502-3p, and KMT5A mRNA in tumor tissues after overexpression or knockdown of LINC00473. e Western blot analysis of cyclin D1, CDK2, and KMT5A expression in tumor tissues. *P < 0.05, **P < 0.01, data represent the mean ± SD.

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