Table 1 M6A regulate miRNAs in different cancers.
From: Interactions between m6A modification and miRNAs in malignant tumors
m6A Regulator | Cancer | miRNAs | Biological function | Ref. |
|---|---|---|---|---|
METTL3 | bladder | miR-221/222 | Promote cells proliferation in bladder | |
METTL3 | colorectal | miR-1246 | Promote cells migration and invasion in CRC | |
METTL3 | pancreatic | miR-25-3p | Promote cells proliferation migration and invasion in pancreatic cancer | |
METTL3 | NSCLC | miR-143-3p | Promote cells invasion in NSCLC | |
Mettl14 | breast | miR-146a-5p | Promote cells migration and invasion in breast cancer | |
Mettl14 | hepatoma | miR-126 | Suppress cells migration in HCC | |
Mettl14 | colorectal | miR-375 | Suppress cells proliferation invasion and migration in CRC | |
ALKBH5 | ovarian | miR-7 | Promote cells proliferation, invasion, and autophagy in ovarian cancer | |
NKAP | pancreatic | miR-25-3p | Promote cells proliferation migration and invasion in pancreatic cancer | |
HNRNPA2B1 | NSCLC | miR-106b-5p | Promote cells proliferation in NSCLC | |
HNRNPC | glioblastoma | miR-21 | Promote cells migration and invasion in glioblastoma |