Table 2 MiRNAs regulate m6A key proteins in different cancers.
From: Interactions between m6A modification and miRNAs in malignant tumors
miRNAs | Cancer | mRNAs | Biological function | Ref. |
|---|---|---|---|---|
miR-33a | NSCLC | METTL3 | Suppress cells proliferation in NSCLC | |
Let-7g | breast | METTL3 | Suppress cells proliferation in breast cancer | |
miR-600 | NSCLC | METTL3 | Suppress cells proliferation migration and promote apoptosis in NSCLC | |
miR-4429 | gastric | METTL3 | Suppress cells proliferation induce apoptosis in gastric cancer | |
miR-186 | hepatoma | METTL3 | Suppress cells proliferation invasion and migration in hepatoma | |
miR-1266 | colorectal | FTO | Suppress cells proliferation in colorectal cancer | |
miR-346 | glioblastoma | YTHDF1 | Suppress cells proliferation and tumor growth in glioblastoma | |
miR-145 | hepatoma | YTHDF2 | Suppress cells proliferation in hepatoma | |
miR-493-3p | prostate | YTHDF2 | Suppress cells proliferation and migration in prostate cancer | |
miR-744-5p | ovarian | HNRNPC | Promote cells apoptosis in ovarian cancer |