Fig. 7: PRDX2 knockdown retards tumor growth by inducing p53 upregulation. | Cell Death & Disease

Fig. 7: PRDX2 knockdown retards tumor growth by inducing p53 upregulation.

From: PRDX2 promotes the proliferation of colorectal cancer cells by increasing the ubiquitinated degradation of p53

Fig. 7: PRDX2 knockdown retards tumor growth by inducing p53 upregulation.

A Images of xenograft tumors harvested at the end of the experiment. **p < 0.05, by two-tailed t-test. B Growth curve of tumor in the NC group and the shPRDX2 group in nude mice. C Tumor weight of the NC group and the shPRDX2 group in nude mice. D p53 and Ki67 were detected in tumors by ICH. E The protein levels of PRDX2 and p53 in 5 tumor samples were measured by western blotting with the indicated primary antibodies. F the working model summarizes the research.

Back to article page