Table 1 The relationship between ISL1 expression and clinical–pathological features in 57 NB patients from our department.

From: ISL1 promoted tumorigenesis and EMT via Aurora kinase A-induced activation of PI3K/AKT signaling pathway in neuroblastoma

Clinical

characteristics

Total no. of patients

No. of patients

χ2

P-value

  

Lower (n = 28)

Higher (n = 29)

  

Sex

 Male

32

16

16

0.022

0.88 

 Female

25

12

13

  

Age

 <18 months

12

4

8

1.516

0.218

 ≥18 months

45

24

21

  

Relapse

 No

34

20

14

3.173

0.075

 Yes

23

8

15

  

INSS stage

 1, 2, 4 s

10

7

3

2.115

0.146

 3, 4

47

28

29

  

COG risk group

 Low risk

3

2

1

10.493

0.005

 Intermediate risk

8

8

0

  

 High risk

46

18

28

  

LDH

 ≥245

42

18

24

2.507

0.113

 <245

15

10

5

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