Fig. 1: FAM64A is upregulated in prostate cancer tissues and cell lines.
From: FAM64A is an androgen receptor-regulated feedback tumor promoter in prostate cancer
a The expression of FAM64A in PCa tissues was significantly higher than that in normal prostate tissues by TCGA. b–d The expression of FAM64 mRNA was related to the T grade, Gleason score, and lymph nodes metastasis. e, f The lower expression level of FAM64A led to longer overall survival time and disease-free survival time. g, h FAM64A was remarkably increased in PCa cell lines PC-3, LNCaP, 22Rv1, and DU145 compared to P69 at both transcription and translation levels. i, j The expression of FAM64A protein in PCa was higher than that in adjacent normal PCa tissues and was related to the Tumor stage by immunohistochemistry staining. Scale bar = 20.25 μm. *P < 0.05, **P < 0.01, ***P < 0.001.
