Table 2 Correlation between FAM64A expression and the clinicopathological characters of patients with prostate cancer (TCGA).

From: FAM64A is an androgen receptor-regulated feedback tumor promoter in prostate cancer

Clinico-pathologic variables

No. of cases

FAM64a expression

X2

P

Low

High

All cases

499

249 (44.3%)

250 (55.7%)

  

Age

≤60

224 (44.9%)

122 (24.5%)

102 (20.4%)

3.3871

0.0657

>60

275 (45.1%)

127 (25.4%)

148 (29.7%)

  

Clinical stage

T1–T2

350 (86.6%)

188 (46.5%)

162 (40.1%)

10.861

0.0010***

T3–T4

54 (13.4%)

16 (4.0%)

38 (9.4%)

  

Lymph nodes status

Negative

328 (80.4%)

161 (39.5%)

167 (40.9%)

5.1321

0.0235*

Positive

80 (19.6%)

28 (6.9%)

52 (12.7%)

  

Gleason score

6–7

295 (59.1%)

176 (35.3%)

119 (23.8%)

27.501

<0.0001***

8–10

204 (40.9%)

73 (14.6%)

131 (26.3%)

  

PSA

429 (96.6%)

213 (48.0%)

216 (48.6%)

0.6210

0.4307

+

15 (3.4%)

9 (2.0%)

6 (1.4%)

  

Survival times (years)

≤5

414 (83%)

217 (43.5%)

197 (39.5%)

6.1521

0.0131*

>5

85 (17%)

32 (6.4%)

53 (10.6%)

  
  1. Pearson’s X2 test.
  2. *P values < 0.05, ***P values < 0.001.