Fig. 3: PSMC2 regulates ovarian cancer cell apoptosis through regulating apoptosis-related proteins and Akt pathway. | Cell Death & Disease

Fig. 3: PSMC2 regulates ovarian cancer cell apoptosis through regulating apoptosis-related proteins and Akt pathway.

From: PSMC2/CCND1 axis promotes development of ovarian cancer through regulating cell growth, apoptosis and migration

Fig. 3

A An apoptosis antibody array was used to detect the differential expression of 43 apoptosis-related proteins in shPSMC2 and shCtrl cells. B 8 of the 43 apoptosis-related proteins were significantly downregulated in shPSMC2 cells. C The expression of Akt, p-Akt, CCND1, CDK6 and CDK1 in shPSMC2 and shCtrl cells was detected by western blotting. Data were presented as mean ± standard deviation based on at least 3 independent experiments. *P < 0.05, **P < 0.01.

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