Fig. 5: PSMC2 regulates ovarian cancer development through CCND1. | Cell Death & Disease

Fig. 5: PSMC2 regulates ovarian cancer development through CCND1.

From: PSMC2/CCND1 axis promotes development of ovarian cancer through regulating cell growth, apoptosis and migration

Fig. 5

A Microarray analysis was performed to identify the upregulated and downregulated genes in shPSMC2 cells. B, C Several downregulated DEGs were selected for qPCR (B) and western blotting (C) verification. D A PSMC2-centered molecular interaction network established based on IPA displayed the potential interaction between PSMC2 and CCND1. E The expression of CCND1 in ovarian cancer tissues and normal tissues was detected by IHC. Data were presented as mean ± standard deviation based on at least 3 independent experiments. *P < 0.05.

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