Fig. 3: Lnc049808 knockdown inhibited TNBC progression.
From: Melatonin inhibits triple-negative breast cancer progression through the Lnc049808-FUNDC1 pathway
A LncRNA microarray analyses were performed on 4T1 and 891 melatonin-treated breast cancer cells. B The expression levels of the top five overlapping downregulated lncRNAs were determined by qRT-PCR. C qRT-PCR showed that lnc049808 knockdown was successful with sh-049808#1. D A CCK-8 assay was performed after transfection in 4T1, 891, and BT549 TNBC cells. E A colony formation assay was performed (upper), and the results were quantified (lower). F A Transwell assay was performed (upper), and the results were quantified (lower). G Representative images of xenograft tumors were shown (upper), and tumor weight was quantified (lower, n = 3 per group). H H&E-stained sections of metastatic lung nodules were shown (left), and the number of metastatic nodules was quantified (right, n = 3 per group). *p < 0.05, **p < 0.01.
