Fig. 1: KAT2A is up-regulated in PC tissues and is correlated with worse prognosis. | Cell Death & Disease

Fig. 1: KAT2A is up-regulated in PC tissues and is correlated with worse prognosis.

From: KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer

Fig. 1

A–C The expression levels of KAT2A in adjacent/normal and tumour were searched in GEO, TCGA, Oncomine respectively. D, E Specimens were stratified into “GS < 8 group” and “GS ≥ 8 group” according to Gleason score (GS), followed by random selection of 6 samples from each group for subsequent western blot experiments. (N: normal, T: tumour). F The correlation between KAT2A, AR expression level and Gleason score were identified by IHC with 54 patients in the “GS < 8 group” and 33 patients in “GS ≥ 8 group”. G–I OS, DFS, PFS were analysed according to high or low expression of KAT2A and log-rank t test was used. J The correlation of KAT2A expression and biochemical recurrence. K The correlation of KAT2A expression and Gleason score. *p < 0.05, **p < 0.01, ***p < 0.001.

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