Fig. 1: hsa_circ_0003222 predicted a negative prognosis in NSCLC patients. | Cell Death & Disease

Fig. 1: hsa_circ_0003222 predicted a negative prognosis in NSCLC patients.

From: hsa_circ_0003222 accelerates stemness and progression of non-small cell lung cancer by sponging miR-527

Fig. 1

A hsa_circ_0003222 level from 30 NSCLC tumor tissues and adjacent non-tumor tissues. B Overall survival of NSCLC in relation to hsa_circ_0003222 level. C The expression of hsa_circ_0003222 in NSCLC was examined by in situ hybridization on an NSCLC tissue microarray analysis (TMA) (74 cases). D LARP4 gene and hsa_circ_0003222 genomic loci. E, F Flow cytometry determination of the proportion of PC9 and A549 lung cancer stem cells (LCSCs) expressing CD44. G Spheroid formation was assessed in PC9 and A549 LCSCs. H RT-qPCR demonstrating hsa_circ_0003222 level in PC9 and A549 or LCSCs. I Western blot demonstrating PD-L1 level in PC9 and A549 cells or LCSCs. Data were shown as mean ± SD; ***P < 0.001.

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