Fig. 2: Cytosolic zinc affects the progression of the fat body cell dissociation. | Cell Death & Disease

Fig. 2: Cytosolic zinc affects the progression of the fat body cell dissociation.

From: Fear-of-intimacy-mediated zinc transport controls fat body cell dissociation through modulating Mmp activity in Drosophila

Fig. 2

A, B The fat body cell dissociation was greatly delayed in Lsp2-Gal4 > foi RNAi while accelerated in Lsp2-Gal4 > foi OE. C, D Dietary zinc supplementation was able to rescue the retarded fat body cell dissociation induced by fat body-specific foi RNAi, while enhance the precocious the progression induced by foi OE. E, F Zinc chelator TPEN had the capability of rescuing the precocious fat body cell dissociation induced by foi OE, while aggravating the retarded fat body cell dissociation induced by foi RNAi. G, H ZnT1 OE in the fat body dramatically rescued the precocious cell dissociation caused by fat body-specific foi OE, while enhanced the retarded cell dissociation induced by foi RNAi. All the experiments were conducted independently at least for 3 times. ns: not significant, *P < 0.05, **P < 0.01, ***P < 0.001, two-tailed Student’s t test.

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