Fig. 3: Foi is required for the structural stabilization of fat body cells. | Cell Death & Disease

Fig. 3: Foi is required for the structural stabilization of fat body cells.

From: Fear-of-intimacy-mediated zinc transport controls fat body cell dissociation through modulating Mmp activity in Drosophila

Fig. 3

The fat body structure was investigated with four hallmarks at the wandering stage, 4 h APF and 7 h APF. A Phalloidin staining revealed the shape of the fat body cells. B, C Immunostaining of DE-cadherin (B) and integrin βPs (C) were used to monitor the cell–cell junctions and cell–basement membrane (BM) junctions, respectively. D Viking-GFP revealed the integrity of the BM. A nearly intact BM was observed in the fat body of Lsp2-Gal4 > foi RNAi animals, while the BM was broken in Lsp2-Gal4 > foi OE animals. w1118 flies driven by Lsp2-Gal4 serve as a blank control. The arrows in (A–C) indicated the gaps between cells, and the arrows in (D) showed the degraded BM.

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