Fig. 2: Ltbp4S deficiency aggravates tubulointerstitial fibrosis in mice.
From: LTBP4 affects renal fibrosis by influencing angiogenesis and altering mitochondrial structure
Wild-type (WT) and Ltbp4S knockout (Ltbp4S−/−) mice were subjected to unilateral ureteral obstruction (UUO) to induce tubulointerstitial fibrosis for five days. A Representative histological images with Masson’s trichrome and immunofluorescence staining of kidneys after UUO. Scale bars, 100 μm. Computer-assisted quantitative analyses of histological images for fibronectin (B) and α-SMA (C) are shown. Data are presented as the mean ± SEM. n = 8–10 mice per group. *p < 0.05, **p < 0.01.
