Fig. 4: CNVs analysis of LUAD patients at different stages.

A High frequently mutated genes in CSF and primary lung tumors are shown. Mutation frequencies in the group are shown on the left. CNV counts (number of CNV events) for each patient is shown at the top. B Comparison of mutation frequencies of CNV genes between CSF and the other three groups, respectively. Significantly different genes were calculated by two-sided Fisher’s exact test. *P < 0.05, **P < 0.01, ***P < 0.001.