Fig. 5: Modulation of the cytokine response of MVA-infected macrophages by distinct cell death-pathways. | Cell Death & Disease

Fig. 5: Modulation of the cytokine response of MVA-infected macrophages by distinct cell death-pathways.

From: Diversity of cell death signaling pathways in macrophages upon infection with modified vaccinia virus Ankara (MVA)

Fig. 5

a–h Supernatants of d7 differentiated wt (black bars) or Bax/Bak-DKO (gray bars) Hoxb8 macrophages infected with MVA at a MOI of 2 were collected after 22 h. Some samples were treated with inhibitors QVD (20 µM) and Nec-1 (10 µM) alone or in combination as indicated. Samples were analysed for the cytokines indicated by a bead-based assay (Legendplex, antivirus response panel, Biolegend). Shown are the means/SEM of n = 3 independent experiments. *p < 0.05; **p < 0.01, ***p < 0.001, ****p < 0.0001; ns nonsignificant (p ≥ 0.05).

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