Fig. 3: ANXA7 expression positively regulates SRI expression and affects EMT in HCC cells. | Cell Death & Disease

Fig. 3: ANXA7 expression positively regulates SRI expression and affects EMT in HCC cells.

From: AnnexinA7 promotes epithelial–mesenchymal transition by interacting with Sorcin and contributes to aggressiveness in hepatocellular carcinoma

Fig. 3

A–D Upregulated ANXA7 increased SRI expression and downregulated ANXA7 decreased SRI expression at the mRNA level in Huh-7 and Hep3B cells (**p < 0.01,*p < 0.05). E–H Upregulated ANXA7 increased SRI expression at the protein level and promoted EMT, whereas downregulated ANXA7 decreased SRI expression at the protein level and inhibited EMT in Huh-7 and Hep3B cells (**p < 0.01,*p < 0.05). I–J IF was used to detect E-cadherin and cytokeratin. K, L IF assay was used to detect the N-cadherin and Vimentin in Huh-7/Hep3B cells.

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