Fig. 6: Linc-ROR increased the progression and angiogenesis via DEPDC1 in HCC cells.

a Cell proliferation was assessed daily for 4 days using the Cell Counting Kit-8 (CCK-8) assay in Linc-ROR overexpressing HepG2 and Hep3B cells. b EdU assays were performed to analyze the HepG2 and Hep3B cell proliferation in differently transfected groups. c Transwell assays were used to evaluate the involvement of Linc-ROR for invasion in Linc-ROR overexpressing HepG2 and Hep3B cells. d Effect of Linc-ROR expression in HepG2 and Hep3B cells on human umbilical vein endothelial cells (HUVECs) in tube formation assay. Each bar represents the mean values ± SD of three independent experiments. e, f Cell proliferation assessed in Linc-ROR knockdown HepG2 and Hep3B cells. g Transwell assays assessed in Linc-ROR knockdown HepG2 and Hep3B cells. h Tube formation assay assessed in Linc-ROR knockdown HepG2 and Hep3B cells. Data are shown as mean ± SD, n = 3. The data statistical significance is assessed by Student’s t test. *P < 0.05, **P < 0.01, ***P < 0.001. Scale bars: 50 μm.