Fig. 7: Carcinogenesis of Linc-ROR requires DEPDC1 in vivo. | Cell Death & Disease

Fig. 7: Carcinogenesis of Linc-ROR requires DEPDC1 in vivo.

From: RETRACTED ARTICLE: Linc-ROR facilitates progression and angiogenesis of hepatocellular carcinoma by modulating DEPDC1 expression

Fig. 7

a−d Representative images, in vivo growth curve, HE, Ki-67 and DEPDC1 immunostaining, and weight at the end points of subcutaneous xenograft tumors formed by HepG2 cells stably transfected with Lv-NC + Lv-shNC, Lv-ROR or Lv-ROR + Lv-shDEPDC1 in nude mice (n = 4 per group). Scale bar, 100 μm. e, f In vivo representative images, HE, Ki-67 and DEPDC1 immunostaining, and metastatic counts of lungs of nude mice (n = 3 per group) treated with tail vein injection of HepG2 cells stably transfected with Lv-NC + Lv-shNC, Lv-ROR or Lv-ROR + Lv-shDEPDC1. Scale bar, 50 μm. g Linc-ROR promoted angiogenesis by the CAM angiogenesis analysis in HepG2 cells. Data are shown as mean ± SD, n = 3. The data statistical significance is assessed by Student’s t test. *P < 0.05, **P < 0.01, ***P < 0.001.

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