Table 1 Correlation between ONECUT2 expression and clinicopathological characteristics of HCCs in two independent cohorts of human HCC tissues.

		Cohort I			Cohort II
Clinicopathological variables		Tumor ONECUT2 expression		P value	Tumor ONECUT2 expression		P value
Clinicopathological variables		Negative (n = 137)	Positive (n = 149)	P value	Negative (n = 84)	Positive (n = 96)	P value
Age		51.77 (9.160)	53.36 (8.559)	0.301	50.46 (10.155)	51.64 (10.53)	0.882
Sex	Female	18	29	0.155	14	18	0.845
Sex	Male	119	120		70	78
Serum AFP	≤20 ng/ml	51	44	0.209	15	27	0.115
Serum AFP	>20 ng/ml	86	105		69	69
Virus infection	HBV	101	103	0.710	65	68	0.431
	HCV	11	18		9	8
	HBV + HCV	7	8		2	5
	None	18	20		8	15
Cirrrhosis	Absent	41	56	0.211	27	24	0.322
Cirrrhosis	Present	96	93		57	72
Child-pugh score	Class A	116	135	0.150	65	72	0.730
Child-pugh score	Class B	21	14		19	24
Tumor number	Single	76	63	0.033*	46	29	0.001*
Tumor number	Multiple	61	86		38	67
Maximal tumor size	≤5 cm	91	77	0.012*	44	36	0.052
Maximal tumor size	>5 cm	46	72		40	60
Tumor encapsulation	Absent	33	54	0.029*	25	57	<0.001*
Tumor encapsulation	Present	104	95		59	39
Microvascular invasion	Absent	88	70	0.004*	63	38	<0.001*
Microvascular invasion	Present	49	79		21	58
Tumor differentiation	I–II	102	92	0.023*	67	49	<0.001*
Tumor differentiation	III–IV	35	57		17	47
TNM stage	I–II	116	96	<0.001*	80	63	<0.001*
TNM stage	III	21	53		4	33

Quick links

Search