Fig. 1: AOPPs accumulation is associated with the enhanced osteoclastogenesis in aged mice. | Cell Death & Disease

Fig. 1: AOPPs accumulation is associated with the enhanced osteoclastogenesis in aged mice.

From: Age-related accumulation of advanced oxidation protein products promotes osteoclastogenesis through disruption of redox homeostasis

Fig. 1: AOPPs accumulation is associated with the enhanced osteoclastogenesis in aged mice.

A Serum AOPPs level significantly increased in aged mice (18-month-old) compared with the young mice (3-month-old). B The serum bone resorption markers, such as TRAP (left Y axis), NTX (left Y axis) and CTX (right Y axis), were significantly increased in aged mice. C TRAP staining of tibia showed the increase of TRAP positive cells in aged mice. Data were presented as mean ± SD. *p < 0.05 versus the young group.

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