Fig. 2: Tumor-derived EVs induce invasion and migration of GC cells. | Cell Death & Disease

Fig. 2: Tumor-derived EVs induce invasion and migration of GC cells.

From: Tumor-derived extracellular vesicles shuttle c-Myc to promote gastric cancer growth and metastasis via the KCNQ1OT1/miR-556-3p/CLIC1 axis

Fig. 2: Tumor-derived EVs induce invasion and migration of GC cells.

A The morphology of EVs observed by a TEM (×10000). B Analysis of particle size of EVs by NanoSight nanoparticle tracking analyzer. C The expression of CD9, CD63, CD81, Calnexin, and TSG101 in GC cells and EVs detected by Western blot analysis. D Observation of internalized EVs in GC cells by immunofluorescence staining. E The migration of GC cells detected by scratch test. F The invasion of GC cells detected by Transwell assay. * represents the comparison between the two groups. *p < 0.05; **p < 0.01; ***p < 0.001.

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