Table 1 Correlation between LRG1 expression and clinicopathological parameters of CRC.
Clinicopathologic features | Number | LRG1 expression(IHC) | ||
|---|---|---|---|---|
High | Low | p value | ||
Gender | ||||
Male | 89 | 44 | 45 | 0.776 |
Female | 52 | 27 | 25 | |
Age(years) | ||||
<65 | 77 | 40 | 37 | 0.678 |
≥65 | 64 | 31 | 33 | |
Tumor size(cm) | ||||
<5 | 19 | 5 | 14 | 0.024 |
≥5 | 122 | 66 | 56 | |
Degree of differentiation | ||||
Highly | 23 | 9 | 14 | 0.239 |
Moderately and poorly | 118 | 62 | 56 | |
Depth of invasion | ||||
T1 + T2 | 27 | 9 | 18 | 0.049 |
T3 + T4 | 114 | 62 | 52 | |
Lymphonodus metastasis | ||||
N0 | 74 | 31 | 43 | 0.035 |
N1, N2 | 67 | 40 | 27 | |
Distance metastasis | ||||
Negative | 118 | 55 | 63 | 0.044 |
Positive | 23 | 16 | 7 | |
Plasma CEA level (preoperative) | ||||
≤5ng/ml | 84 | 33 | 51 | 0.013 |
>5ng/ml | 42 | 27 | 15 | |
Plasma CA19-9 level (preoperative) | ||||
≤37u/ml | 98 | 47 | 51 | 0.811 |
>37u/ml | 21 | 9 | 12 | |
