Fig. 2: Overexpression of CEMIP is correlated with unfavorable pathological characteristics in PCa. | Cell Death & Disease

Fig. 2: Overexpression of CEMIP is correlated with unfavorable pathological characteristics in PCa.

From: ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells

Fig. 2

A Western blot analysis of the expression level of CEMIP in anoikis-resistant and parental PC-3 and DU145 cells. B Western blot analysis of the expression level of CEMIP in PC-3 cells at different suspension time points (0–72 h). C Immumohistochemical staining demonstrated the expression level of CEMIP in PCa tissues and corresponding pericarcinous specimens (Original magnification, ×400). D The expression of CEMIP in PCa tissues and corresponding adjacent tissues was presented by histochemistry score (n = 60, *p < 0.05, **p < 0.01). E qRT-PCR analysis of the mRNA level of CEMIP in 14 pairs of human PCa and their adjacent normal tissues. F Western blot analysis of the protein level of CEMIP in 14 pairs of PCa tissues and corresponding pericarcinous counterparts. G Western blot analysis of the protein expression level of CEMIP in prostatic epithelial cells (RWPE-1) and different PCa cells (LNCaP, 22RV1, PC-3, DU145). (Data are presented as the means ± SD of three independent experiments; *p < 0.05, **p < 0.01).

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