Fig. 6: HERC3 regulates the EMT via EIF5A2/TGF-/Smad2/3 signal. | Cell Death & Disease

Fig. 6: HERC3 regulates the EMT via EIF5A2/TGF-/Smad2/3 signal.

From: HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer

Fig. 6

Western blotting (a and b) indicated that EIF5A2 overexpression could rescue the effects of HERC overexpression on EMT and TGF-/Smad2/3 signal in HCT116 cells and EIF5A2 downregulation could also rescue the effects of HERC3 downregulation on EMT and TGF-/Smad2/3 signal in SW620 cells. Experiments were conducted with indicated cell lines.

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