Fig. 5: DLEU2 effected prostate cancer progression via the miR-582-5p/SGK1 axis. | Cell Death & Disease

Fig. 5: DLEU2 effected prostate cancer progression via the miR-582-5p/SGK1 axis.

From: E2F transcription factor 2-activated DLEU2 contributes to prostate tumorigenesis by upregulating serum and glucocorticoid-induced protein kinase 1

Fig. 5

A Western blot analysis of SGK1 expression in DLEU2 knockdown PC-3, DU145 cells transfected with miR582-5p inhibitor or SGK1 overexpression vector. B, C The cell viability of PC-3 and DU145 cells as described above. D Result of EdU assay showing the cell proliferation in PC-3 and DU145 cells as described above (scale bar: 50 μm). E The colony formation analysis of PC-3 and DU145 cells as described above. F The migration and invasion analysis of prostate cancer cells as described above (scale bar: 50 μm). Data were indicated as mean ± SD, ns P ≥ 0.05, *P < 0.05, **P < 0.01, ***P < 0.001.

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