Fig. 7: Knockdown of DLEU2 suppressed prostate tumor growth in vivo. | Cell Death & Disease

Fig. 7: Knockdown of DLEU2 suppressed prostate tumor growth in vivo.

From: E2F transcription factor 2-activated DLEU2 contributes to prostate tumorigenesis by upregulating serum and glucocorticoid-induced protein kinase 1

Fig. 7

A The tumor growth curve of xenografts was plotted in shNC and shDLEU2 group (n = 6 each group) by measuring the tumor size (0.5 × length × width2) each 5 days. B The subcutaneous tumor models were observed at 35 days in two different groups. C Images of xenograft tumors of each group (n = 6). D Weight of xenograft tumors of each group (n = 6). E Representative HE staining, IHC staining of Ki-67, SGK1 and FISH of DLEU2, miR-582-5p in tumor xenografts were conducted (scale bar: 50 μm). F The IHC scores of Ki-67, SGK1 and FISH scores of DLEU2, miR-582-5p in tumor xenografts. Data were indicated as mean ± SD, ns P ≥ 0.05, *P < 0.05, **P < 0.01, ***P < 0.001.

Back to article page