Fig. 3: RNA-sequence analysis of CRC cells and colorectal CSCs. | Cell Death & Disease

Fig. 3: RNA-sequence analysis of CRC cells and colorectal CSCs.

From: ZNF32 promotes the self-renewal of colorectal cancer cells by regulating the LEPR-STAT3 signaling pathway

Fig. 3: RNA-sequence analysis of CRC cells and colorectal CSCs.The alternative text for this image may have been generated using AI.

(A) Heat map of 2718 differentially expressed genes between bulk cells and colorectal CSCs (SW480 and pCRC1 vs CSCs-SW480 and CSC-pCRC1). Each column represents one sample; each row represents one probe set. Red indicates upregulated expression, while green indicates downregulated expression. The image is one represent of three independent experiments. (B) A volcano plot was arranged using the fold change and P value. The red rectangle represents differentially expressed genes between bulk cells and colorectal CSCs, P < 0.05, fold change ≥ 2.0. The image is one represent of three independent experiments. (C) GO analysis of upregulated genes between bulk cells and colorectal CSCs. The data presented here are from one representative experiment of three independent experiments. (D) GO analysis of downregulated genes between bulk cells and colorectal CSCs. The data presented here are from one representative experiment of three independent experiments. (E) KEGG pathway analysis of upregulated genes between bulk cells and colorectal CSCs. The data presented here are from one representative experiment of three independent experiments. (F) KEGG pathway analysis of downregulated genes between bulk cells and colorectal CSCs. The data presented here are from one representative experiment of three independent experiments.

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