Fig. 7: ACLY/P300 mediates Nanog expression to drive CRC cell dormancy.
From: Nanog mediated by FAO/ACLY signaling induces cellular dormancy in colorectal cancer cells
A, B Dormancy markers could be inhibited by ACLY inhibition and reversed by Nanog overexpression in SF HT29 cells. C, D Dormancy markers could be inhibited by P300 inhibition and reversed by Nanog overexpression in SF HT29 cells. E CD31 (green) and Nanog (red) expression in subcutaneous tumors of mouse and CRC tissues by Immunofluorescence. The stained sections were observed under a fluorescent microscope and photographed. Scale bar = 50 μm. Data are shown as the means ± s.e.m., n = 3; *P < 0.05, **P < 0.01, ***P < 0.001. Data shown represented three independent experiments.
