Fig. 3: MiR-7682-3p was direct target of circRNA_37492. | Cell Death & Disease

Fig. 3: MiR-7682-3p was direct target of circRNA_37492.

From: The mmu_circRNA_37492/hsa_circ_0012138 function as potential ceRNA to attenuate obstructive renal fibrosis

Fig. 3

A CircRNA_37492 contained the complementary binding region sequence of miR-7682-3p. B After co-transfection with vector of circRNA_37492-WT or circRNA_37492-MT and miR-7682-3p mimic or scramble, the luciferase activities were detected. C The co-localization of circRNA_37492 and miR-7682-3p in BUMPT cells treated with TGF-β1. Scale bar, 10 μm. D The co-localization of circRNA_37492 and miR-7682-3p in kidney tissue of C57BL/6 mice subjected to UUO. Scale bar, 50μm. Quantitative data are presented as the mean ± SD (n = 6 per group). *p < 0.05, circRNA_37492 WT with miR-7682-3p vs. other groups. MT, mutant type; WT, wild type.

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