Fig. 3: Overexpression CCDC12 enhances the biological behavior of tumor cells.
From: CCDC12 promotes tumor development and invasion through the Snail pathway in colon adenocarcinoma
A Increase in colony formation in colon cancer cells (100×). B The proportion of cells blocked in the G0/G1 phase was reduced. C Increase in cell migration ability (200×). D Increase in invasion ability (200×). E Apoptosis rates of cells were reduced. F The volumes and weights of xenograft tumors were significantly increased. G IHC and H&E stain for the expression of key EMT molecules in xenograft tumor (40×). H Liver metastatic nodules with their IHC staining (40×). (* <0.05; ** <0.01; *** <0.001; **** <0.0001).
