Fig. 1: Genome-wide detection of eccDNAs in FaDu/DDP and FaDu cells. | Cell Death & Disease

Fig. 1: Genome-wide detection of eccDNAs in FaDu/DDP and FaDu cells.

From: Encoding gene RAB3B exists in linear chromosomal and circular extrachromosomal DNA and contributes to cisplatin resistance of hypopharyngeal squamous cell carcinoma via inducing autophagy

Fig. 1

A Number of eccDNA types and involved genes from FaDu/DDP and FaDu cells are depicted according to the cell lines. B Schematic representation of the mechanism of different types of eccDNA amplifying the same gene. C Number of genes derived from 1, 2, 3, 4, 5, 6, 7 or 8 different types of eccDNAs in FaDu/DDP cells. D Number of genes derived from 1, 2, 3, 4, 5, 6, 7 or 8 different types of eccDNAs in FaDu cells. E Schematic representation of the mechanism by which different types of eccDNAs amplify more than one gene. F Number of eccDNA types amplifying 1, 2, 3, 4, 5, 6, 7 or 8 different genes in FaDu/DDP cells. G Number of eccDNA types amplifying 1, 2, 3, 4, 5, 6, 7 or 8 different genes in FaDu cells. H Size of eccDNA ranged from 0.01 kb to 1000 kb in FaDu/DDP cells. I Size of eccDNA ranged from 0.01 kb to 1000 kb in FaDu cells.

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