Fig. 4: The role of adipose tissue in the aging process.
From: Adipose tissue aging: mechanisms and therapeutic implications
In aging individuals, the adipose tissue can be characterized by tissue redistribution, reduced brown and beige fat, declined APSCs, senescent cell accumulation with SASP, and dysregulated immune cells. Aging adipose impacts the elderly with ectopic lipid and FFA, dysregulated adiponectin, increased proinflammatory cytokines, reduced miRNA synthesis, and high ROS activity. This figure was created in part with modified BioRender templates.
