Fig. 1: NFATc3 is mainly located in the nucleus in PDAC specimens and indicates poorer prognosis.
From: Hypoxia-induced NFATc3 deSUMOylation enhances pancreatic carcinoma progression
a Expression and location of NFATc3 in 60 samples of human PDAC tissues and matched adjacent normal tissues by IHC staining with an anti-NFATc3 antibody. Representative images are shown. Scale bars, 10 μm. b Comparative analysis of nuclear NFATc3 expression between PDAC tissues and matched adjacent normal tissues (***P < 0.001). c Correlations between nuclear NFATc3 expression levels and PDAC clinicopathological parameters. d Kaplan–Meier plots and p-values of the log-rank test for comparing survivals of PDAC patients with high (staining score, 5–12) and low (staining score, 0–4) expression of nuclear NFATc3.
