Fig. 1: High HJURP and YAP1 expression in TNBC cells. | Cell Death & Disease

Fig. 1: High HJURP and YAP1 expression in TNBC cells.

From: HJURP regulates cell proliferation and chemo-resistance via YAP1/NDRG1 transcriptional axis in triple-negative breast cancer

Fig. 1

A Western blot analysis of HJURP and YAP1 expression in breast cancer cell lines (MCF-7, T47D, ZR-75-1, SK-BR-3, MDA-MB-231, BT549, HS578T, HCC1937, and BCAP-37). B, C Oncomine database showed the expression of HJURP and YAP1 in normal breast tissues, triple-negative breast cancer, and non-triple-negative breast cancer. D Kaplan–Meier analyses RFS based on HJURP and YAP1 mRNA levels, using the KM-plotter breast cancer database (http://kmplot.com/analysis/). A median cutoff was chosen in the analysis. E, F The expression of HJURP in MAD-MB-231 cells and BT549 cells stably transfected with or without HJURP shRNAs was explored by western blot analysis and RT-PCR analysis. Data were presented as mean ± SD of three independent experiments. *p < 0.05; **p < 0.01; ns not significant.

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