Fig. 8: Various therapeutic approaches that may eradicate LCSCs.
From: Mechanism of cancer stemness maintenance in human liver cancer

LCSCs liver cancer stem cells, EMT epithelial–mesenchymal transition, MET mesenchymal-to-epithelial transition, TAMs tumor-associated macrophages, TANs tumor-associated neutrophils, CAFs cancer-associated fibroblasts, LECs lymphatic endothelial cells, SBHA suberoyl bis-hydroxamic acid, CAR-T chimeric antigen receptor T-cell immunotherapy.