Fig. 7: Proposed mechanism scheme of LHPP in GC. | Cell Death & Disease

Fig. 7: Proposed mechanism scheme of LHPP in GC.

From: m6A methylation mediates LHPP acetylation as a tumour aerobic glycolysis suppressor to improve the prognosis of gastric cancer

Fig. 7: Proposed mechanism scheme of LHPP in GC.The alternative text for this image may have been generated using AI.

The m6A modification of LHPP mRNA by METTL14 represses its expression; LHPP inhibits the phosphorylation of GSK3b through acetylation and mediates HIF1A to inhibit glycolysis, proliferation, invasion and metastasis of gastric cancer cells.

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