Fig. 1: UHMK1 was overexpressed in CRC and significantly associated with poor prognosis. | Cell Death & Disease

Fig. 1: UHMK1 was overexpressed in CRC and significantly associated with poor prognosis.

From: UHMK1 aids colorectal cancer cell proliferation and chemoresistance through augmenting IL-6/STAT3 signaling

Fig. 1: UHMK1 was overexpressed in CRC and significantly associated with poor prognosis.

A UHMK1 mRNA level was higher in colon adenocarcinoma tissues than normal tissues (TCGA-COAD dataset, http://gepia.cancer-pku.cn/). B UHMK1 was upregulated in tumor tissues compared with normal tissues in colorectal carcinoma samples from Hong’cohort and colon adenocarcinoma tissues from Kaiser’s cohort. C Expression scores of UHMK1 in colon cancer tissues were higher than corresponding non-tumor tissues in a tissue microarray, p < 0.001. D Representative IHC images of UHMK1 in colon cancer tissues and adjacent normal colon tissues. Scale bar: 25 μm. E Representative IHC images indicating high expression or low expression of UHMK1 in colon cancer tissues. Scale bar: 25 μm. F Kaplan–Meyer plot of two groups of CRC patients classified by UHMK1 expression. Statistical analyses were performed with log-rank test (P = 0.02). Red, high expression group; black, low expression group.

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