Table 1 Correlations of WNT5A and SNAIL expression with the clinicopathological characteristics of patients with ESCC.

From: WNT5A promotes the metastasis of esophageal squamous cell carcinoma by activating the HDAC7/SNAIL signaling pathway

Clinicopathological variables

n

WNT5A expression

 

SNAIL expression

 

Low

High

P value

Low

High

P value

Age

   

0.480

  

0.795

<60

45

24

21

 

21

24

 

≥60

100

47

53

 

49

51

 

Gender

   

0.752

  

0.289

Female

26

12

14

 

15

11

 

Male

119

59

60

 

55

64

 

Smoking history

   

0.293

  

0.398

Never

57

31

26

 

30

27

 

Ever

88

40

48

 

40

48

 

Tumor size

   

0.724

  

0.127

<5 cm

49

25

24

 

28

21

 

≥5 cm

96

46

50

 

42

54

 

TNM stages

   

0.038

  

0.025

I–II

71

41

30

 

41

30

 

III–IV

74

30

44

 

29

45

 

Tumor invasion

   

0.832

  

0.316

T1–T2

13

6

7

 

8

5

 

T3–T4

132

65

67

 

62

70

 

Lymphatic invasion

   

0.023

  

0.005

N0

78

45

33

 

46

32

 

N1–N3

67

26

41

 

24

43

 

Differentiation

   

0.727

  

0.533

Well and moderate

128

62

66

 

63

65

 

Poorly and not

17

9

8

 

7

10