Fig. 1: The expression of Cx43 correlates with the severity of kidney injury. | Cell Death & Disease

Fig. 1: The expression of Cx43 correlates with the severity of kidney injury.

From: Blocking connexin 43 and its promotion of ATP release from renal tubular epithelial cells ameliorates renal fibrosis

Fig. 1: The expression of Cx43 correlates with the severity of kidney injury.The alternative text for this image may have been generated using AI.

A Scheme. time-related comparison after UUO and BIR. B PAS staining. PAS staining was executed to evaluate renal tubular injury by calculating damaged tubules. C Immunofluorescence. Cx43-positive tubules were counted at different points. D The percentage (left) and number (right) of Cx43-positive tubules analyses by flow cytometry from the whole kidneys. E Immunofluorescence. The immunofluorescence co-staining of NCC (a collecting tubule cells specific marker), KSP (a renal tubular epithelial cell-specific marker), LTL (a proximal tubule cells specific marker) or DBA (a distal tubule cells specific marker) with Cx43. Data are presented as the mean ± SEM, n = 4–7/group, *P < 0.05, **P < 0.01, ***P < 0.001; Scale bar: 100 μm.

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