Fig. 1: DGE analysis of colorectal cells transfected with Ant-NC and Ant-823.
From: piR-823 inhibits cell apoptosis via modulating mitophagy by binding to PINK1 in colorectal cancer
A The relative piR-823 level of human CRC cell lines HCT116 and DLD-1 transfected with Ant-NC or Ant-823 by real-time PCR. B Differentially expressed genes (DEGs) were detected in different groups (P < 0.05). The red part, green part, and blue part represented the upregulated genes, downregulated genes, and genes without expression difference respectively in Ant-823 group compared to control group. C The top 20 genes that were most dysregulated by piRNA-823 antagomir treatment. D The differentially expressed genes mapped to the autophagy database. E The expression changes of mitophagy and autophagy-related proteins after inhibition of piR-823. *P < 0.05, **P < 0.01 vs control groups.
