Fig. 4: Inhibition of mitophagy alleviated piR-823 inhibition-induced mitochondrial dysfunction and loss. | Cell Death & Disease

Fig. 4: Inhibition of mitophagy alleviated piR-823 inhibition-induced mitochondrial dysfunction and loss.

From: piR-823 inhibits cell apoptosis via modulating mitophagy by binding to PINK1 in colorectal cancer

Fig. 4

A Mitochondrial potential changes detected via JC-1 staining. B Western blot analysis of Parkin, pS65-Parkin, HSP90, COX IV, and TOM20 in HCT116 and DLD-1 cells transfected with siNC or siParkin in combination with Ant-NC or Ant-823 for 72 h. *P < 0.05, **P < 0.01, ***P < 0.001 vs control groups.

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